DRF : Sujet de thèse SL-DRF-20-0397
In this thesis we propose to contribute to an ambitious detector based on Cherenkov/Scintillating crystals. We have selected technologies that are particularly effective for PET imaging. The principles of the detector are patented. They will allow one to produce neurological PET with highly improved performances. The device uses advanced particles detector technologies: a dense scintillator crystal, micro-channel plate photomultipliers, gigahertz bandwidth amplifiers and fast data acquisition modules (WaveCatcher, SAMPIC). Data processing will involve Monté-Carlo simulations and data analysis based on GATE/Geant4 and Root C++ software libraries.
Positron emission tomography (PET) is a nuclear imaging technique widely used in oncology and neurobiological research. Decay of the radioactive tracer emits positrons, which annihilate in the nearby tissue. Two gamma quanta of 511 keV energy are produced by positron annihilation and allow one to reconstruct the annihilation vertex and distribution of the tracer activity in the body of the patient.
The precise determination of the position of the positron annihilation vertex is important for an accurate image reconstruction with a good contrast. In particular, it is useful for neuroimaging studies of brain and for pre-clinical studies with animal models (rodents).
You will calibrate and optimize the detector prototypes and analyze the measured data. Your will be focussing on detector time and spatial resolution optimization. This will involve many skills of an instrument scientist : fast photo-detection, fast electronics read-out (analog and digital) with picosecond precision, hardware and detector simulations with GEANT4 and GATE software.
Knowledge in physics of particle interaction with matter, radioactivity and particle detector principles, a vocation for instrumental (hardware) work, data analysis are mandatory. Being comfortable in programming, having a background in Gate/Geant4 simulation and C++ will be an asset.
You will acquire skills in particle detector instrumentation, simulation of ionizing radiation detectors, photo-detection, implementation, operation of fast digitizing electronics, and data analysis.
Dominique Yvon : email@example.com
Viatcheslav Sharyy : firstname.lastname@example.org
M2, Advanced detector intrumentation, Particle or Nuclear Physics, Medical Physicist
Service de Physique des Particules
Groupe Santé et Energie (GSE)
Centre : Saclay
Date souhaitée pour le début de la thèse : 01/10/2020
Physique et Ingénierie: électrons, photons et sciences du vivant (EOBE)
DSM, IRFU, DPhP