DSM : Thesis SL-DSM-15-0360

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Research field

Analytic chemistry / Solid state physics, chemistry and nanosciences
Physical chemistry and electrochemistry / Solid state physics, chemistry and nanosciences

Title

Cryogenic Magic Angle Spinning Dynamic Nuclear Polarization: pushing the limits of sensitivity in solid-state Nuclear Magnetic Resonance

Abstract

The SCIB at INAC (Institute for Nanosciences and Cryogenics, CEA Grenoble) has a PhD opening for a physical-chemist. This PhD deals with the development of a new and emerging technique called solid-state MAS-DNP (Magic Angle spinning Dynamic Nuclear Polarization). This hyperpolarization technique allows recording solid-state NMR (Nuclear Magnetic Resonance) spectra that can be used to extract structural information such as: surface functionalization, inter-nuclei distances, etc.

This technique has recently proven particularly useful when applied to systems that cannot be solved using X-ray crystallography or solution-state NMR. Thanks to huge time-savings (several orders of magnitude!!) one can now start studying very challenging systems (such as porous materials, self-assembled nano-assemblies, silicon nanoparticles/nanowires, etc.) which were so far lacking efficient atomic scale characterization techniques.

This PhD will take place in a highly dynamical environment at the MINATEC campus (CEA Grenoble) within the SCIB laboratory (CEA INAC) where the DNP group, in collaboration with the Bruker company (world leader in NMR instrumentation), is currently pushing the development and use of this technique (high field Dynamic Nuclear Polarization) beyond its state-of-the-art. The group is working with the first High Field MAS-DNP system installed in France (since September 2011) and has successfully conducted instrumental and methodological developments over the last three years.

Overall, we aim to demonstrate that with several orders of magnitude of additional sensitivity gain, solid-state Magic Angle Spinning Dynamic Nuclear Polarization performed at very low temperature (10-100 K) has the potential to address significant problems for systems where other well-established spectroscopies (X-ray, solution-state NMR, etc.) cannot be applied.

This PhD work will take place within a larger ANR funded project (ANR blanc 2012-2016, PI G. De Paëpe) involving a strong partnership between two academic laboratories (INAC/CEA and LNCMI/CNRS) and an industrial partner (Bruker Biospin).

Location

Institut nanosciences et cryogénie
Service de Chimie Inorganique et Biologique
Laboratoire de Résonance Magnétique
Centre : Grenoble
Starting date : 01/10/2015

Contact person

Daniel LEE
CEA / DSM/INAC/SCIB/RM
INAC/SCIB/RM

CEA Grenoble

17 rue des Martyrs

38054 Grenoble cedex 9
Phone : 04 38 78 65 84

More about

http://inac.cea.fr/Pisp/gael.depaepe/

University / Graduate School

Grenoble I (UJF)
Chimie et Sciences du Vivant (EDCSV) - Grenoble I -

Thesis supervisor

GAEL DE PAEPE
CEA / DSM/INAC/SCIB/RM
INAC/SCIB/RM

CEA Grenoble

17 rue des Martyrs

38054 Grenoble cedex 9


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